ActoFactor™ Human Glial Cell-Derived Neurotrophic Factor (HEK293)
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- Q & A
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Cat.No.
CSC-CTK0372G
Description
Glial Cell-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that supports the survival and differentiation of neurons, particularly dopaminergic neurons. It has potential therapeutic applications in neurodegenerative diseases like Parkinson’s disease.
Species
Human
Source
HEK293
GeneID
2668
Accession Number
P39905
N-terminal Sequence
Met-Arg134-Arg-Gly-Glu-Leu-Ser-Val-(Cys)-Asp
Synonymous Name
GDNF, Glial Cell Line-Derived Neurotrophic Factor
Molecular Mass
Approximately 22 to 25 kDa (reduced) and 30 to 38 kDa (non-reduced), a homodimeric glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The specific activity is minimally 1.00x10⁶ IU/mg, typically 1.30x10⁶ IU/mg.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile 1x PBS pH 7.4 containing 0.1% endotoxin-free recombinant human serum albumin (HSA) of less than 0.2 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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