ActoFactor™ Human FLT3L
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Cat.No.
CSC-CTK0392G
Description
FLT3L is essential for the development of dendritic cells (DCs), influencing T cell immunity and tolerance. It is produced as a membrane-bound protein and can be cleaved into a soluble form. FLT3L levels are elevated in conditions like rheumatoid arthritis and during infections, highlighting its role in immune regulation and disease progression.
Species
Human
Source
CHO
GeneID
483845
Synonymous Name
FLT3L, FLT3 Ligand, Fms-like Tyrosine Kinase 3 Ligand
Molecular Mass
Approximately 27-34 kDa (reduced) and 23-30 kDa (non-reduced), a monomeric glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The ED50 for FLT3L, which induces IL-6 production in mouse myeloid leukemia M1 cells in a dose-dependent manner in the presence of 1 ng/mL of mouse LIF recombinant protein, is between 1 and 6 ng/mL.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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