ActoFactor™ Human Bone Morphogenetic Protein 7 (E. coli)
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Cat.No.
CSC-CTK0388G
Description
BMP-2 is a growth factor involved in bone and cartilage formation. It induces osteogenic differentiation and cartilage repair. BMP-2 signals through serine/threonine kinase receptors and activates downstream pathways. Recombinant Human BMP-2 is produced with pharmaceutical-grade materials and follows GMP standards.
Species
Human
Source
E. coli
GeneID
650
Synonymous Name
BMP-2, Bone Morphogenetic Protein 2, BMP2A
Molecular Mass
The DTT-reduced and non-reduced protein migrates at approximately 13 and 26 kD respectively by SDS-PAGE.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The ED50 for BMP-2, which induces alkaline phosphatase (ALP) production in the mouse chondrogenic cell line ATDC5 in a dose-dependent manner, is between 40 and 200 ng/mL. The specific activity of the Human BMP-2 is ≥ 1.4 x 10⁵ IU/mg.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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