ActoFactor™ Human Bone Morphogenetic Protein 7 (CHO)
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Cat.No.
CSC-CTK0391G
Description
BMP-7 is a multifunctional growth factor within the TGF-β superfamily. It forms homodimers and heterodimers with BMP-2 and BMP-4, enhancing activity in embryonic development. BMP-7 acts as an anti-fibrotic agent, counteracting TGF-β1-induced fibrosis in various organs. It also plays a role in cancer progression and has potential therapeutic applications in tissue repair and fibrosis management.
Species
Human
Source
CHO
GeneID
655
Accession Number
P18075
Synonymous Name
BMP-7, Bone Morphogenetic Protein 7, OP-1 (Osteogenic Protein-1)
Molecular Mass
Approximately 20 kDa (reduced) and 32 to 36 kDa (non-reduced), a homodimeric glycosylated polypeptide chain.
Size
10ug, 100μg, 500μg, 1000μg, Custom
Purity
>95%
Activity
Fully biologically active when compared to standard. The ED50 for BMP-7, which induces alkaline phosphatase (ALP) production in the mouse chondrogenic cell line ATDC5 in a dose-dependent manner, is between 18 and 72 ng/mL.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Usage
This GMP product can be for research use or further manufacturing use.(NOT FOR HUMAN USE)
Storage
Store lyophilized cytokine at -20°C to -80°C.
Shipping
Dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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