ActoFactor™ Recombinant Human Growth & Differentiation Factor 7

CSC-CTK0541

GDF-7 belongs to the TGF-β superfamily of growth and differentiation factors. It is expressed selectively by roof plate cells that are located in the developing embryonic central nervous system, and has been shown to influence the neuronal identity of cells within the central nervous system. GDF-7 has also been implicated in the formation, maintenance, and repair of certain cartilage and ligament tissue. Recombinant human GDF-7 is a 28 kDa disulfide linked homodimer containing two 129 amino acid residues.

Human

Human GDF7 expressed in E.coli

28 kDa

CAT# CSC-CTK0541-10 (10 μg); CAT# CSC-CTK0541-50 (50 μg)

E.coli

Greater than 98% as determined by HPLC and SDS-PAGE analysis.

Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.

Less than 1 EU/μg.

Sterile filtered through a 0.2 micron filter and lyophilized from 10 mM citric acid.

Please centrifuge product briefly before opening vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.

The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.