Three isoforms of the neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform (1102-1150 a.a.) is the basic molecule which is glycosylated or sialylated to produce the mature species. NCAM (CD56) is reported to be expressed on most neuroectodermal derived cell lines and tissues as well as neoplasms such as retinoblastoma, medullblastoma, astrocytoma and neuroblastoma. It is also expressed on some mesodermally derived tumors such as rhabdomyosarcoma and also on natural killer cells.
Human NCAM1 expressed in E.coli
CAT# CSC-CTK0310-2 2 μg; CAT# CSC-CTK0310-10 (10 μg)
Greater than 90% as determined by SDS-PAGE and HPLC analysis.
Sterile-filtered, clear solution. Recombinant prote in at 100 μg/ml in 50 mM Tris-acetate (pH 7.5), 1 mM EDTA and 20% glycerol without BSA and sodium azi de.
Storage & Stability
Please Note: Always centrifuge product briefly before opening vial. Store vial at –20°C to –80°C. When stored at the recommended temperature, this protein is stable for 12 months. Avoid repeated freeze-thaw cycles.
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