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Immortalized Human Cardiomyocytes-SV40

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Cat.No.
CSC-I9071L
Description
Human Cardiomyocytes are isolated from human heart ventricles. Their specialized high-oxygen-content with a large number of mitochondria contributes to the major role of cardiac muscles in the heart’s rhythmic pumping. Cardiomyocytes are regulated by a complex network of signals. Cardiomyocytes hypertrophy and apoptosis have been associated with the loss of contractile function during heart failure. They are ideal models for study of cytokines and cellular signaling mechanisms that lead to myocyte death, as well as for research on mechanical strain and cell-cell interaction.
Species
Homo sapiens
Source
Ventricle Tissue
Culture Properties
Adherent
Morphology
Multipolar
Immortalization Method
Serial passaging and transduction with recombinant lentiviruses carrying SV40 Large T antigen
Markers
sarcomeric alpha-actinin, slow muscle myosin
Applications
For Research Use Only
Storage
Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.

Note: Never can cells be kept at -20 °C.
Shipping
Dry Ice.
Recommended Products
CSC-C2847 Human Cardiomyocytes
CIK-HT003 HT® Lenti-SV40T Immortalization Kit
Quality Control
Real Time PCR was used to quantify SV40 gene expression in immortalized cell line.
BioSafety Level
II
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

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