ActoFactor™ Recombinant Mouse Interferon lambda 2
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Cat.No.
CSC-CTK0676
Description
IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant murine IFN-lambda2 is a 19.8 kDa protein containing 175 amino acid residues.
Species
                                Mouse
                            Product Overview
                                Mouse Ifnl2 expressed in E.coli
                            Molecular Mass
                                19.8 kDa
                            Size
                                CAT# CSC-CTK0676-20 (20 μg); CAT# CSC-CTK0676-100 (100 μg)
                            Expression System
                                E.coli
                            Purity
                                Greater than 95% as determined by SDS-PAGE and HPLC analysis.
                            Activity
                                Determined by its ability to activate STAT following receptor-ligand interaction.
                            Endotoxin Level
                                Less than 1 EU/μg.
                            Formulation
                                Lyophilized (freeze-dried), sterile powder. Lyophilized with no additives.
                            Reconstitution
                                Please centrifuge product briefly before opening vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0,1 - 1,0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
                            Storage & Stability
                                The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted rMu IFN-lambda-2 should be used immediately or stored long-term in undiluted working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
                            Citation Guidance
                        
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