Immortalized Rat Hepatic Stellate Cells (HSC-T6)
Cat.No.: CSC-I2673Z
Culture Properties: Adherent
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Cat.No.
CSC-I2673Z
Description
The HSC-T6 cell line is a well-established immortalized model derived from adult rat liver, widely used to study hepatic stellate cell behavior in liver health and disease. These cells are central to understanding liver fibrosis and cirrhosis, as they transition from vitamin A-storing cells into activated myofibroblasts upon injury, driving extracellular matrix deposition and fibrotic scarring.
HSC-T6 cells express hallmark activation markers such as α-SMA, GFAP, and desmin, and demonstrate high proliferative activity along with responsiveness to key cytokines and growth factors. This makes them a robust and reproducible tool for investigating profibrotic signaling pathways and screening anti-fibrotic therapies. Their well-characterized phenotype supports ongoing research into liver disease mechanisms and therapeutic development.
Freezing Medium
Complete medium supplemented with 10% (v/v) DMSO
Recommended Medium
SuperCult® Immortalized Rat Hepatic Stellate Cell Medium
Freezing Medium
Complete medium supplemented with 10% (v/v) DMSO
Culture Properties
Adherent
Quality Control
free from contaminations (bacteria incl. mycoplasma, fungi, HIV, HAV, HBV, HCV, Parvo-B19) and cross-contaminations
Storage and Shipping
Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.
Note: Never can cells be kept at -20°C.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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