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Immortalized Human Pancreatic Duct Epithelial Cells (HPDE6c7)
Cat.No.: CSC-I2298Z
Species: homo sapiens
Morphology: Polygonal
Culture Properties: Adherent
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Cat.No.
CSC-I2298Z
Description
Immortalized Human Pancreatic Duct Epithelial Cells (HPDE6c7) demonstrates a near normal genotype and phenotype of pancreatic duct epithelial cells. Immortalized Human Pancreatic Duct Epithelial Cells (HPDE6c7) retain normal Ki-ras, p53, C-myc, and p16INK4A genotypes but lack the p53 functional pathway.Immortalized Human Pancreatic Duct Epithelial Cells (HPDE6c7) are useful for studies on the molecular basis of pancreatic duct cell carcinogenesis and islet cell differentiation. Immortalized Human Pancreatic Duct Epithelial Cells (HPDE6c7) are a versatile model for the pancreatic ductal epithelium, facilitating the development of strategies for the chemoprevention of human pancreatic cancers.
Immortalized Human Pancreatic Duct Epithelial Cells (HPDE6c7) originated from normal human pancreatic duct of a 63-year-old female, having been genotypically altered by infection with retrovirus vector expressing E6E7 genes of human papilloma virus (HPV)-16.3
Species
homo sapiens
Recommended Medium
SuperCult® Immortalized Human Pancreatic Duct Epithelial Cell Medium (Cat No.: CM-I2298Z)
Freezing Medium
Complete medium supplemented with 10% (v/v) DMSO
Culture Properties
Adherent
Morphology
Polygonal
Application
For Research Use Only
Growth Properties
Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO2.
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