FTC-133
Cat.No.: CSC-6254W
Species: Homo sapiens (Human)
Source: Thyroid Gland
Morphology: Polymorphic
Culture Properties: adherent
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Cat.No.
CSC-6254W
Description
FTC-133 was isolated from a lymph node metastasis of a follicular thyroid carcinoma. The morphology differs from flat polygonal to spindle formed cells. They retained differentiated thyrocyte function and thyrocyte responsiveness to thyrotropin and local active growth factors. Thyroglobulin immunoreactivity could be shown in the cytoplasm and EGF receptor immunoreactivity could be visualised on the cell membranes. Complex chromosomal changes were detected as well as a p53 mutation.
Species
Homo sapiens (Human)
Source
Thyroid Gland
Recommended Medium
Culture Properties
adherent
Morphology
Polymorphic
STR DNA Profile
Amelogenin: X
CSF1PO: 10
D13S317: 11
D16S539: 11
D5S818: 12
D7S820: 9,10
THO1: 9.3
TPOX: 9
vWA: 15,18
CSF1PO: 10
D13S317: 11
D16S539: 11
D5S818: 12
D7S820: 9,10
THO1: 9.3
TPOX: 9
vWA: 15,18
Karyotype
Complex chromosomal changes
Application
Function of human thyroid and development of thyroid cancer.
Disease
Thyroid Gland Follicular Carcinoma
Quality Control
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
liquid nitrogen vapor phase
Synonyms
FTC133
Citation Guidance
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