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Immortalized Rat Lymphocytes (Nb2-11)
Cat.No.: CSC-I2313Z
Species: rat
Culture Properties: Suspension
- Specification
- Q & A
- Customer Review
Cat.No.
CSC-I2313Z
Description
Immortalized Rat lymphocytes (Nb2-11) is a clone of the Nb-2 rat lymphoma line which was derived from a transplant of a lymphoma that developed in the thymus/lymph node of a male noble (Nb) strain rat following prolonged oestrogen treatment. The cells are of the pre-T cell origin and their proliferation is dependent on mammalian lactogens, such as prolactin. Nb2-11 can also be mitogenically stimulated by IL-2. Injection of Nb2 cells into Nb rats gives rise to malignant tumours that are highly sensitive to treatment with vinca alkaloids. Karyotypic analysis has shown that the cell line has only five well developed chromosome abnormalities. The cells do not express surface immunoglobulin, and their lactogen dependency was confirmed before deposit.
Species
rat
Tissue of Origin
Rat lymph
Recommended Medium
SuperCult® Immortalized Rat Lymphocyte Medium (Cat No.: CM-I2313Z)
Freezing Medium
Complete medium supplemented with 10% (v/v) DMSO
Culture Properties
Suspension
Application
For Research Use Only
Growth Properties
Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO2.
Storage
Store in liquid nitrogen
Shipping
Ship in dry ice
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
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