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Immortalized MS-/- Mouse Alveolar Macrophage Cells (ZK6)
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Cat.No.
CSC-I9331L
Description
Alveolar macrophages were isolated from the brochoalveolar lavage fluid of MARCO-/-SR-AI/II-/-(MS-/-) mice and were immortalized with the J2 retrovirus to establish the Immortalized MS-/-Mouse Alveolar Macrophage Cells (ZK6). ZK26cells exhibit the macrophage morphology, functional activity, and the ability to bind to and ingest particles are reduced due to the deficiency in MARCO and SR-AI/II scavenger receptors. It is a valuable tool to study the functions of MARCO and SR-AI/II scavenger receptors and particle toxicity.
Species
Mus musculus
Source
Brochoalveolar
Culture Properties
Adherent
Morphology
Polygonal
Immortalization Method
Infected with J2 retrovirus supernatants collected from the AMJ2-C11 cell line which carries the vraf and vmyc oncogenes
Applications
For Research Use Only
Storage
Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.
Note: Never can cells be kept at -20 °C.
Note: Never can cells be kept at -20 °C.
Shipping
Dry Ice.
Recommended Products
CIK-HT003 HT® Lenti-SV40T Immortalization Kit
Quality Control
PCR genotyping used to determine the deficiency of MARCO and SR-AI/II.
BioSafety Level
II
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
CSC-I9001L
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