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Immortalized Mouse Lung Clara Cells-SV40 (mTCC)

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Cat.No.
CSC-I9198L
Description
Clara cells play a role in the maintenance of normal bronchiolar epithelium by secreting Clara Cell Secretory Proteins (i.e. CC10) to protect the respiratory tract against oxidative stress and inflammation. The Immortalized Mouse Lung Clara Cells- SV40 (mTCC) was generated form the lungs of transgenic mouse expressing SV40 Large T antigen under the control of a Clara cell-specific (CCSP) promoter. This cell line expresses SP-B and CC10 and is useful in studying lung epithelial physiology and pulmonary inflammation.
Species
Mus musculus
Source
Lung
Culture Properties
Adherent
Immortalization Method
SV40 Large T antigen under a CCSP promoter
Markers
SP-B, CC10
Applications
For Research Use Only
Storage
Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.

Note: Never can cells be kept at -20 °C.
Shipping
Dry Ice.
Recommended Products
CIK-HT003 HT® Lenti-SV40T Immortalization Kit
Quality Control
1) Presence of CC10 and SP-B were confirmed via northern blot analysis;
2) Presence of SV40 Large T Antigen was confirmed via northern blot analysis.
BioSafety Level
II
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

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