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Immortalized Adult Mouse Cogulating Gland Cells (INK4 -/- CG)
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Cat.No.
CSC-I9256L
Description
The Immortalized Adult Mouse Cogulating Gland Cells (INK4 -/- CG)are derived from a subline of the INK4a mouse, a transgenic knockout that lacks p16INK4aand p19ARF. Both p16INK4aand p19ARFare specific inhibitors of cyclin-dependent kinases Cdk4 and Cdk6 that regulate cell cycle progression. The cells were isolated from the anterior prostate (AP), also known as the coagulating gland (CG), which has a unique cuboidal to columnar epithelium that has many mucosal folds projecting into the gland lumen. The lumen contains abundant eosinophilic secretions from the luminal secretory cells in the epithelium. This cell line is a useful model for studying the prostate stroma-epithelium signalling way, which plays an important role in prostate development and cancer progression.
Species
Mus musculus
Source
Dorsolateral Prostate
Culture Properties
Adherent
Morphology
Fibroblast-like
Immortalization Method
Isolated from p16INK4aand p19ARFKnockout Transgenic Mice
Applications
For Research Use Only
Storage
Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.
Note: Never can cells be kept at -20 °C.
Note: Never can cells be kept at -20 °C.
Shipping
Dry Ice.
Recommended Products
CIK-HT003 HT® Lenti-SV40T Immortalization Kit
BioSafety Level
II
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
CSC-I9001L
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