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OPM-2
- Specification
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Cat.No.
CSC-C0222
Description
Established from the peripheral blood of a 56-year-old woman with multiple myeloma (IgG lambda) in leukemic phase (relapse, terminal) in 1982; described to carry t(4;14) leading to IGH@-FGFR3 (IGH-FGFR3; IGH-MMSET) fusion gene
Source
multiple myeloma
Culture Properties
suspension
Morphology
single, round to polygonal cells in suspension
Karyotype
Human hypertriploid/hypotetraploid karyotype - 78(77-82)<3n>XX-X, +1, +1, +1, +2, +4, +5, -7, +9, +11, -14, +15, +16, +18, +19, -21, +2-3mar, add(1)(p11), add(1)(q11)x2, del(1)(p11)x2, del(1)(q32), t(4;14)(p16;q32.3), der(4)t(4;14)(p16;q32.3), add(5)(q11)
Quality Control
Mycoplasma: negative in DAPI, microbiological culture, PCR assays
Immunology: CD3 -, CD10 -, CD19 -, CD20 -, CD34 -, CD37 -, CD38 +, CD80 -, CD138 +, HLA-DR -, sm/cyIgG -, sm/cyIgM -, sm/cykappa -, sm/cylambda -
Viruses: ELISA: reverse transcriptase negat
Immunology: CD3 -, CD10 -, CD19 -, CD20 -, CD34 -, CD37 -, CD38 +, CD80 -, CD138 +, HLA-DR -, sm/cyIgG -, sm/cyIgM -, sm/cykappa -, sm/cylambda -
Viruses: ELISA: reverse transcriptase negat
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 3.5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
How is the cell cycle regulated?
A:
Cell-cycle control depends exclusively on post-transcriptional mechanisms that involve the regulation of Cdk activity by phosphorylation and the binding of regulatory proteins such as cyclins, which are themselves regulated by proteolysis.
Average Rating: 5.0 | 1 Scientist has reviewed this product
Impressive quality and speed
The tumor cell products arrived faster than expected and the quality is exceptional.
14 Aug 2022
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