Description
Established from the peripheral blood of a 38-year-old man with chronic myeloid leukemia (CML) in myeloid blast crisis; described to express basophilic features and to carry t(9;22) leading to BCR-ABL1 e14-a2 (b3-a2) fusion gene.
Organism
Homo sapiens, human
STR DNA Profile
Amelogenin: X,Y
CSF1PO: 12,13
D13S317: 8
D16S539: 9
D18S51: 13
D21S11: 30,31,2
D3S1358: 15
D5S818: 10
D7S820: 12
D8S1179: 11,15
FGA: 22,24
Penta D: 12
Penta E: 5,19
THO1: 9
TPOX: 12
vWA: 15
D18S51: 13
Penta E: 14,16
Penta D: 11,13
D8S1179: 10
FGA:
Karyotype
58, XY, t(9;22)(q34;q11), i(17q), +1, +4, +6, +6, +8, +der(9)t(9;22), + der(9)t(9;22), +der(11)q(11), +14, +15, +19, +21, +21, -9
Culture Properties
Suspension
Quality Control
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
liquid nitrogen vapor phase
Disease
Chronic myelogenous leukemia
Application
This cell line can be used in chromosome and tumourigenicity studies.
Citation Guidance
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