JURL-MK2

Cat.No.: CSC-C0541

Species: Human

Source: chronic myeloid leukemia in blast crisis

Morphology: round single cells growing in suspension, heterogenous in size, occasional giant cells

Culture Properties: suspension

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Cat.No.

CSC-C0541

Description

Established from the peripheral blood of a 73-year-old man with chronic myeloid leukemia (CML) in blast crisis in 1993; cells carry the Philadelphia chromosome; JURL-MK1 and JURL-MK2 are sister cell lines derived from the same patient

Species

Human

Source

chronic myeloid leukemia in blast crisis

Recommended Medium

85% RPMI-1640 + 15% h.i. FBS

Culture Properties

suspension

Morphology

round single cells growing in suspension, heterogenous in size, occasional giant cells

Karyotype

Human hypotetraploid karyotype with 3.5% polyploidy - 81(77-82)<4n>XXYY, -2, -7, -12, +13, -14, -14, -16, -18, -19, -22, +1-3mar, add(9)(q1)x2, der(9)del(9)(p21.2)t(9;22)(q34;q11)x2, der(11)t(11;9;22)(p15;q34;q11)x2, add(17)(p13)x1-2, der(22)t(9;22)(q34;q

Quality Control

Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD4 -, CD13 +, CD19 -, CD30 +, CD33 +, HLA-DR +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 8 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

What are IHC biomarkers?

IHC is a hugely popular tool in cancer research and remains the gold standard in clinical cancer diagnostics. Each different type of cancer is associated with specific protein biomarkers that can be identified via IHC to offer a powerful tool to investigate tumor development and responses.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

Reliable choice

Cell contamination can confound experimental results. I buy my cells from Creative Bioarray because their products have been rigorously validated.

23 Aug 2022

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For research use only. Not for any other purpose.