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CFPAC-1
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Cat.No.
CSC-C8213L
Description
This cell line is a ductal pancreatic adenocarcinoma derived by differential trypsinisation of explant cultures from a metastatic lesion in the liver of a 26 year old caucasian male with cystic fibrosis (CF). The cell line expresses cystic fibrosis trans-membrane regulator (CFTR) and ion transport properties consistent with the CF defect. The cells express the CF gene and show the most common CF mutation, deletion of three nucleotides result in a phenylalanine-508 deletion. CFPAC-1 cells are also tumorigenic in nude mice.
Species
Homo sapiens (human)
Tissue of Origin
Pancreas
Recommended Medium
80% SuperCult® IMDM + 20% h.i. FBS.
Culture Properties
Adherent
Morphology
Epithelial
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
What are the markers used to identify tumor stem cells?
A:
Different types of tumors express specific markers associated with tumor stem cells. For example, CD133 is often used as a marker for tumor stem cells in brain tumors, while CD44 and ALDH1 are used in breast cancer.
Average Rating: 5.0 | 1 Scientist has reviewed this product
Useful
We have successfully utilized the tumor cell product to study the effects of various therapeutic modalities on tumor angiogenesis.
10 May 2023
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