CFPAC-1

Cat.No.: CSC-C8213L

Species: Homo sapiens (human)

Morphology: Epithelial

Culture Properties: Adherent

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Cat.No.

CSC-C8213L

Description

This cell line is a ductal pancreatic adenocarcinoma derived by differential trypsinisation of explant cultures from a metastatic lesion in the liver of a 26 year old caucasian male with cystic fibrosis (CF). The cell line expresses cystic fibrosis trans-membrane regulator (CFTR) and ion transport properties consistent with the CF defect. The cells express the CF gene and show the most common CF mutation, deletion of three nucleotides result in a phenylalanine-508 deletion. CFPAC-1 cells are also tumorigenic in nude mice.

Species

Homo sapiens (human)

Tissue of Origin

Pancreas

Recommended Medium

80% SuperCult® IMDM + 20% h.i. FBS.

Culture Properties

Adherent

Morphology

Epithelial

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

What are the markers used to identify tumor stem cells?

Different types of tumors express specific markers associated with tumor stem cells. For example, CD133 is often used as a marker for tumor stem cells in brain tumors, while CD44 and ALDH1 are used in breast cancer.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

Useful

We have successfully utilized the tumor cell product to study the effects of various therapeutic modalities on tumor angiogenesis.

10 May 2023

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