Abundantly present on AML blasts, CD33 and CD123, are one of the promising targets for CAR T-cell therapy. In particular, CD123 has been identified as a marker of leukemia-initiating cells also expressed by other hematologic malignancies. The Anti-CD123 CAR-T Cell ISH Probe targeting the CAR 3’ UTR allows for highly sensitive and especific detection of Anti-CD123 CAR-T cells.
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