Short Stature Xp22 Probe

FMDC-36

The SHOX (Short stature Homeobox-containing gene) is located at Xp22 and Yp11.3 in the pseudoautosomal region (PAR1) of both chromosomes. It encodes a transcription factor of 292 and 225 amino acids (SHOXa and SHOXb respectively) whose translated proteins differ in the C-terminal region. SHOX is a cell-specific homeodomain protein involved in cell cycle and growth regulation and activates transcription in the osteogenic cells. The incidence of SHOX deficiency is between 1 in 2000 to 1 in 5000 in the general population, and 1 in 40 to 1 in 150 in short people.

5 Tests, 10 Tests

Red/Green

Human

Xp22/Yp11.3

For Research Use Only. Not for use in diagnostic procedures.

Store at minus 20 centigrade

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