The SHOX (Short stature Homeobox-containing gene) is located at Xp22 and Yp11.3 in the pseudoautosomal region (PAR1) of both chromosomes. It encodes a transcription factor of 292 and 225 amino acids (SHOXa and SHOXb respectively) whose translated proteins differ in the C-terminal region. SHOX is a cell-specific homeodomain protein involved in cell cycle and growth regulation and activates transcription in the osteogenic cells. The incidence of SHOX deficiency is between 1 in 2000 to 1 in 5000 in the general population, and 1 in 40 to 1 in 150 in short people.
For Research Use Only. Not for use in diagnostic procedures.
Store at minus 20 centigrade
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.