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SUP-M2
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Cat.No.
CSC-C0518
Description
Derived from the cerebrospinal fluid of a 5-year-old girl with refractory malignant histiocytosis; described to carry the typical t(2;5)(p23;q35) leading to the NPM1-ALK (NPM-ALK) fusion gene and to express CD30, defining the cells as anaplastic large cell lymphoma (ALCL)
Species
Human
Source
anaplastic large cell lymphoma
Culture Properties
suspension
Morphology
round cells growing singly or in clumps in suspension
Karyotype
Human flat-moded near-diploid karyotype with 3.5% polyploidy - 44-50<2n>XX/XXX, +1, +7, +8, add(X)(q26), der(X;7)(q10;p10), add(1)(q21), der(1)(1pter->q43::1q43->q21::9q31->qter), t(2;5)(p23;q35), der(6)t(6;6)(q27;p11), add(9)(q31), add(11)(q24)/der(11)t(
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD2 +, CD3 -, CD4 +, CD13 -, CD14 -, CD19 -, CD21 -, CD25 +, CD30 +, CD34 -, CD71 +, HLA-DR +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Immunology: CD2 +, CD3 -, CD4 +, CD13 -, CD14 -, CD19 -, CD21 -, CD25 +, CD30 +, CD34 -, CD71 +, HLA-DR +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 7.5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
- Product Information Sheet
Q:
What is tumor monoclonality?
A:
According to educational materials provided by the National Institutes of Health, monoclonal tumor origin means that tumors are derived from a single ancestral cell that underwent conversion from a normal to a cancerous state.
Average Rating: 5.0 | 1 Scientist has reviewed this product
Excellent results
The tumor cells are easy to culture and have provided excellent results in our experiments.
03 Nov 2022
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