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MALT Break Probe
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Cat.No.
FONC-072
Description
Extranodal marginal zone B-cell lymphoma (MZBCL) of the MALT (Mucosa-Associated Lymphoid Tissue) type is characterised by two main translocations involving MALT1; t(11;18)(q21;q21) and t(14;18)(q32;q21). The t(11;18) API2/BIRC3/MALT1 translocation is present in 30% of cases of MALT lymphoma, the fusion protein induces NF-κB resulting in transcription activation. Eighteen percent of MALT lymphomas harbour the t(14;18) MALT1/IGH translocation. A break or split probe for MALT (18q21) is best used to analyze translocation of the MALT gene at 18q21.
Size
10 Tests
Label
Red/Green
Locus
18q21
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
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