Featured Products
- Adipose Tissue-Derived Stem Cells
- Human Neurons
- Mouse Probe
- Whole Chromosome Painting Probes
- Hepatic Cells
- Renal Cells
- In Vitro ADME Kits
- Tissue Microarray
- Tissue Blocks
- Tissue Sections
- FFPE Cell Pellet
- Probe
- Centromere Probes
- Telomere Probes
- Satellite Enumeration Probes
- Subtelomere Specific Probes
- Bacterial Probes
- ISH/FISH Probes
- Exosome Isolation Kit
- Human Adult Stem Cells
- Mouse Stem Cells
- iPSCs
- Mouse Embryonic Stem Cells
- iPSC Differentiation Kits
- Mesenchymal Stem Cells
- Immortalized Human Cells
- Immortalized Murine Cells
- Cell Immortalization Kit
- Adipose Cells
- Cardiac Cells
- Dermal Cells
- Epidermal Cells
- Peripheral Blood Mononuclear Cells
- Umbilical Cord Cells
- Monkey Primary Cells
- Mouse Primary Cells
- Breast Tumor Cells
- Colorectal Tumor Cells
- Esophageal Tumor Cells
- Lung Tumor Cells
- Leukemia/Lymphoma/Myeloma Cells
- Ovarian Tumor Cells
- Pancreatic Tumor Cells
- Mouse Tumor Cells
Hot Products
CCND1/CEP 11 Probe
- Specification
- Q & A
- Customer Review
Cat.No.
FONC-025
Description
CCND1/CEP 11 FISH Probe Kit to detect CCND1 amplification in breast cancer samples. Al-Karaya et al. analyzed a tissue microarray of 2197 breast cancer samples using the probe kit and found CCND1 amplification in 20.1% of cases. CCND1 amplification was associated with high tumor grade and a tendency toward shortened survival. Jirstrom et al. analyzed a tissue microarray of 500 breast cancer specimens treated and not treated with adjuvant tamoxifen. The study found CCND1 amplification to be agonistic to tamoxifen with a significantly higher risk of recurrence.
The CCND1/CEP11 Probe have been applied to cancers other than breast cancer. For example, Katz et al. found elevated CCND1 copy number to be sensitive indicator of mantle cell lymphoma, and could distinguish mantle cell lymphoma from most other B-cell non Hodgkins lymphoma specimens.
The CCND1/CEP11 Probe have been applied to cancers other than breast cancer. For example, Katz et al. found elevated CCND1 copy number to be sensitive indicator of mantle cell lymphoma, and could distinguish mantle cell lymphoma from most other B-cell non Hodgkins lymphoma specimens.
Size
10 Tests
Label
Red/Green
Specificity
Human
Locus
11q13/SE 11
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
If your paper has been published, please click here
to submit the PubMed ID of your paper to get a coupon.
Ask a Question
Write your own review