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FGFR1 FISH Probe
- Specification
- Q & A
- Customer Review
Cat.No.
FONC-130
Description
FGFR1 FISH Probe is specifically designed to detect amplifications and deletions of the FGFR1 gene. This probe features vibrant orange labeling for enhanced visualization, and we offer customization options to meet your specific research needs.
FGFR1 (Fibroblast Growth Factor Receptor 1) is a member of the fibroblast growth factor receptor family, which plays a crucial role in various biological processes, including cell proliferation, differentiation, and angiogenesis. FGFR1 is involved in signaling pathways that regulate developmental processes and tissue homeostasis. Abnormalities in FGFR1, such as amplifications and mutations, have been implicated in several cancers, including lung cancer, breast cancer, and bladder cancer.
Clinical Relevance: The detection of FGFR1 amplifications and deletions is essential for understanding the molecular mechanisms underlying these malignancies. Aberrant FGFR1 signaling can lead to uncontrolled cell growth and tumor progression. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies, including the use of FGFR inhibitors, which have shown promise in treating tumors with FGFR1 dysregulation.
Our FGFR1 FISH Probe is an indispensable tool for researcher focused on elucidating the role of FGFR1 in cancer biology and advancing personalized medicine approaches.
FGFR1 (Fibroblast Growth Factor Receptor 1) is a member of the fibroblast growth factor receptor family, which plays a crucial role in various biological processes, including cell proliferation, differentiation, and angiogenesis. FGFR1 is involved in signaling pathways that regulate developmental processes and tissue homeostasis. Abnormalities in FGFR1, such as amplifications and mutations, have been implicated in several cancers, including lung cancer, breast cancer, and bladder cancer.
Clinical Relevance: The detection of FGFR1 amplifications and deletions is essential for understanding the molecular mechanisms underlying these malignancies. Aberrant FGFR1 signaling can lead to uncontrolled cell growth and tumor progression. Identifying these genetic alterations can provide valuable insights into disease prognosis and may inform targeted therapeutic strategies, including the use of FGFR inhibitors, which have shown promise in treating tumors with FGFR1 dysregulation.
Our FGFR1 FISH Probe is an indispensable tool for researcher focused on elucidating the role of FGFR1 in cancer biology and advancing personalized medicine approaches.
Size
10 Tests; 20 Tests
Label
Orange/Green/Aqua
Specificity
Human
Locus
8p11.23-p11.22
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade in the dark
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
If your paper has been published, please click here
to submit the PubMed ID of your paper to get a coupon.
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