Vascular endothelial growth factor receptor-2 (VEGFR-2/KDR/Flk-1) is a high-affinity receptor for vascular endothelial growth factor-A (VEGF-A) and mediates most of the VEGF-A related endothelial growth and survival signals. VEGFR-2 is highly expressed on tumor vasculature as well as on certain tumor cells. Vascular endothelial growth factor receptors and the therapeutic targeting of angiogenesis in cancer. The Anti-VEGF-R2 CAR-T Cell ISH Probe targeting the CAR 3’ UTR allows for highly sensitive and especific detection of Anti-VEGF-R2 CAR-T cells.
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