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Cat.No.

CSC-C0554

Description

Established from the peripheral blood of a 5-year-old girl at relapse of acute lymphoblastic leukemia (ALL) in 1990; reported to carry the t(4;11) MLL-AFF1 (MLL-AF4)

Species

Human

Source

B cell precursor leukemia

Recommended Medium

90% SuperCult® IMDM + 10% h.i. FBS.

Culture Properties

suspension

Morphology

round to polygonal single rather small cells in suspension

Karyotype

Human hypodiploid karyotype with 1.5% polyploidy - 45(40-46)<2n>XX, -13, t(4;11)(q21;q23), del(7)(p14) - carries t(4;11) with breakpoints at AFF1 (AF4) and MLL - matches published karyotype

Quality Control

Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3-, CD4-, CD11b-, CD13+, CD14-, CD15+, CD19+, CD33+, CD34-, cyCD68-, HLA-DR+, sm/cyIgG-, sm/cyIgM-, sm/cykappa-, sm/cylamda-
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, S

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

Product Sheets

Datasheet

No 'Material Safety Data Sheet' available yet

CM-1450Y

CS-001Y

For research use only. Not for any other purpose.

Q & A
Customer Review

What is an isolated tumour cell?

Pathologists use the term isolated tumour cells (ITCs) to describe a small group of tumour cells found in a lymph node. To meet this definition, the group of tumour cells usually has to be less than 200 total cells or smaller than 0.2 mm.

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Average Rating: 5.0 | 1 Scientist has reviewed this product

Satisfied

The staff at Creative Bioarray provided me with excellent customer service, and I am very satisfied with the quality of the cells I received.

11 Aug 2022

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