The IGH/MYC/CEP 8 Tri-Color Dual Fusion FISH probes are intended to detect the t(8;14)(q24;q32)reciprocal translocation involving the IGH and MYC gene regions.
The t(8;14)(q24;q32) translocation is a hallmark of Burkitt's Lymphoma (BL) and occurs in about 80% of BL cases. As such, testing for t(8;14)(q24;q32) or variants is indicated as an essential test for BL. The IGH/MYC/CEP 8 Tri-color Dual Fusion probe has been used to identify the t(8;14)(q24;q32) translocation in published reports. The aqua CEP 8 probe serves as a control for the copy number of chromosome 8.
For Research Use Only. Not for use in diagnostic procedures.
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