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HNT-34
- Specification
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Cat.No.
CSC-C0601
Description
Established in 1994 from the peripheral blood of a 47-year-old woman with acute myeloid leukemia (AML FAB M4) secondary to previous myelodysplastic syndromes (MDS), specifically chronic myelomonocytic leukemia (CMML); described to carry the t(3;3)(q21;q26) leading to MECOM (EVI1) overexpression and the Philadelphia chromosome t(9;22) expressing both P190 and P210 BCR-ABL1 chimeric transcripts
Source
acute myeloid leukemia
Culture Properties
suspension
Morphology
round cells growing singly and in clusters in suspension
Karyotype
Human flat-moded near-diploid karyotype with 7% polyploidy; 46(44-48)<2n>XX, t(3;3)(q21;q26), t(9;22)(q34;q11), del(17)( ?p12.2p13.1), del(20)(q13.1q13.2); t(3;3) and t(9;22) effect rearrangement of MECOM (EVI1) and BCR-ABL1, respectively; matches publish
Quality Control
Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD4 +, CD13 +, CD15 +, CD19 -, CD33 +, CD34 +, HLA-DR +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Immunology: CD3 -, CD4 +, CD13 +, CD15 +, CD19 -, CD33 +, CD34 +, HLA-DR +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Q:
What is a karyotype of a tumor cell that can be characterized?
A:
Cancer karyotypes can be distinguished by the level of their complexity, varying from the presence of only one abnormal chromosome in the diploid set of chromosomes up to very complex karyotypes with almost every chromosome structurally rearranged and/or present in abnormal quantity.
Average Rating: 5.0 | 1 Scientist has reviewed this product
Consistent results
We have received consistent results with this tumor cell product, giving us confidence in our research findings.
10 Mar 2023
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