The D5S23, D5S721/CEP 9/CEP 15 FISH Probe Kit is intended to detect the copy number of the D5S23,D5S721, CEP 9 and CEP 15 probe targets located at5p15.2, 9p11.1-q11.1 and 15p11.1-q11.1, respectively,using FISH.
Hyperdiploidy is one of the cytogenetic subgroups of multiple myeloma (MM). In a study of 205 samples, the Vysis D5S23,D5S721/CEP 9/CEP 15 FISH Probe Kit was used to detect hyperdiploidy. Six hundred fifty-seven samples of the IFM99 trial conducted by the Intergroupe Francophone du Mye′lome were also tested for hyperdiploidy using the Vysis D5S23, D5S721/CEP 9/CEP 15 FISH Probe Kit. Of these samples, 39% showed hyperdiploidy.
For Research Use Only. Not for use in diagnostic procedures.
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