Description
CEP 8 is a SpectrumOrange labeled probe specific for the alpha satellite (centromeric) region, 8p11.1-q11.1.
The CEP 8 Probe may be used as an adjunct to standard karotyping to identify and enumerate chromosome 8 in cells obtained from bone marrow. In multi-site trials, the CEP 8 Probe for interphase analysis was 96% sensitive and 98% specific as compared to traditional cytogenetic analysis. A close association has been made between trisomy 8 and both myeloid blast crisis and basophilia. Trisomy 8 is a prevalent genetic aberration in several specific disorders: Chronic Myelogenous Leukemia (CML), Acute Myeloid Leukemia (AML), Myeloproliferative disorders (MPD), Myelodysplastic Syndrome (MDS), Other hematologic disorders not specified (HDNOS).
Locus
8p11.1-q11.1 Alpha Satellite DNA
Usage
For Research Use Only. Not for use in diagnostic procedures.
Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no.
If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
USA: 1-631-626-9181
Europe: 44-207-097-1828
