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KYSE-450

  • Specification
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Cat.No.
CSC-C0435
Description
Established from the well differentiated invasive eosphageal squamous cell carcinoma resected from middle intra-thoracic esophagus of a 59-year-old Japanese man prior to treatment (depth of invasion was not beyond the submucosa); described as carrying p53 mutation and amplification of the oncogene MYC
Species
Human
Source
esophageal squamous cell carcinoma
Recommended Medium
90%RPMI1640 or 45%RPMI1640 + 45%Ham's F-12 + 10%h.i. FBS.
Culture Properties
monolayer
Morphology
epitheloid cells growing adherently as monolayers
Karyotype
Human hyperdiploid karyotype with 6.7% polyploidy - 57(49-57)<2n>, -Y, +1, +3, +3, +7, +12, +17, -18, +7mar, der(1)t(1;6)(p22;q11), add(1)(p32/34), del(2)(p23), del(3)(p22), del(4)(q21), add(5)(q35), del(6)(q25), add(7)(p22), add(8)(p23), add(9)(q34), del
Quality Control
Mycoplasma: contamination was eliminated with BM-Cyclin (tiamulin & minocycline), then negative in DAPI, microbiological culture, RNA hybridization assays
Immunology: cytokeratin +, cytokeratin-7 -, cytokeratin-8 +, cytokeratin-17 +, cytokeratin-18 +, cy
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 3 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

For research use only. Not for any other purpose.

  • Q & A
  • Customer Review
Q:
What cancer cells are found in the esophagus?
A:

Squamous cell carcinoma occurs most often in the upper and middle portions of the esophagus. Squamous cell carcinoma is the most prevalent esophageal cancer worldwide. Other rare types. Some rare forms of esophageal cancer include small cell carcinoma, sarcoma, lymphoma, melanoma and choriocarcinoma.

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Average Rating: 4.0    |    1 Scientist has reviewed this product

Exceed expectation

The quality and purity of the cell products exceeded my expectations, and the customer service team was excellent in helping me with my order.

13 May 2022


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