JURL-MK1

Specification
Recommended Products

Cat.No.

CSC-C0540

Description

Established from the peripheral blood of a 73-year-old man with chronic myeloid leukemia (CML) in blast crisis in 1993; cells carry the Philadelphia chromosome; JURL-MK1 and JURL-MK2 are sister cell lines derived from the same patient

Species

Human

Source

chronic myeloid leukemia in blast crisis

Recommended Medium

90% RPMI-1640 + 10% h.i. FBS

Culture Properties

suspension

Morphology

round cells growing singly or in small clusters in suspension

Karyotype

Human hypodiploid karyotype with 4% polyploidy - 45(41-45)<2n>XY, -9, add(1)(p35), der(9)del(9)(p21.2)t(9;22)(q34;q11), der(11)t(11;9;22)(p15;q34;q11), add(12)(p13)x2, add(17)(p13), der(22)t(9;22)(q34;q11) - carries t(9;22) effecting BCR-ABL1 fusion (two

Quality Control

Mycoplasma: negative in microbiological culture, PCR assays
Immunology: CD3 -, CD4 -, CD13 +, CD15 +, CD33 +, CD34 +, CD41 +, CD42 +, CD71 +, CD116 +, CD117 +, HLA-DR +
Viruses: PCR: EBV -, HBV -, HCV -, HIV -, HTLV-I/II -, SMRV -

Storage and Shipping

Frozen with 70% medium, 20% FBS, 10% DMSO at about 5-8 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen

Citation Guidance

If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.

CM-1448Y

SuperCult® RPMI 1640 Medium

INQUIRY

CS-001Y

PremSera® FBS

INQUIRY

For research use only. Not for any other purpose.