Uterine/Cervix Tumor Cells

Uterine and cervical tumors encompass a diverse range of malignancies, from HPV-associated cervical squamous cell carcinomas and hormone-responsive endometrial adenocarcinomas to rare Müllerian-origin tumors. These cancers exhibit distinct genetic alterations, differentiation states, and therapeutic sensitivities, posing significant challenges for both clinical management and in vitro research.

Our uterine/cervix tumor cell line collection offers a curated set of reliable in vitro models derived directly from human patient specimens. These models accurately reflect the biological complexity of the disease, including HPV integration, estrogen/progesterone receptor expression, and multi-drug resistance phenotypes, providing essential tools for investigating tumor progression, validating targeted therapies, and exploring mechanisms of treatment resistance.

Authentic Diverse Characterized Supported

Product List

Key Features & Expertise

Our uterine/cervix tumor cell lines stand out for the following features

Diverse, Relevant, and Well-Characterized Models
  • Broad coverage of uterine and cervical cancers, including cervical squamous cell carcinoma, endometrial adenocarcinoma, and mixed Müllerian tumors
  • Representation of key biological features such as HPV16 integration and hormone receptor expression
  • Reflect the phenotypic and genetic heterogeneity of human uterine and cervical malignancies
Deep Characterization & Reliable Performance
  • Established from primary patient tumors (e.g., SKN, HeLa S3) and validated for growth characteristics
  • Documented phenotypes such as multi-drug resistance (e.g., MDR in KB-V1) and hormone responsiveness (e.g., HHHUA)
  • Consistent growth behavior suitable for reproducible in vitro studies and high-throughput screening
Quality You Can Trust
  • Rigorously tested to ensure authenticity and quality control
  • Cryopreserved and shipped under optimal conditions for experimental reliability
  • Stable supply with comprehensive technical support for your research needs

FAQ

What types of uterine and cervical tumors are represented in this collection?

This collection includes a variety of histological types such as cervical squamous cell carcinoma (e.g., SKN, TC-YIK), endometrial adenocarcinoma (e.g., HHHUA, EFE-184), and mixed Müllerian tumors (e.g., HTMMT). It covers both HPV-associated and hormone-responsive models.

Are there any HPV-positive cell lines available?

Yes, several cell lines in this collection are HPV-positive, such as TC-YIK (integrating HPV16) and HeLa S3 (originally derived from HPV18-positive cervical cancer). These models are valuable for studying viral oncogenesis and HPV-related therapies.

Which cell lines are suitable for hormone therapy research?

Cell lines expressing estrogen and progesterone receptors, such as HHHUA, are ideal for hormone therapy studies. These models allow researchers to investigate the effects of hormonal signaling on tumor growth and response to endocrine therapy.

Can these cell lines be used for drug resistance studies?

Absolutely. We offer multi-drug resistant variants like KB-V1 (derived from KB-3-1), which are specifically suited for studying chemotherapy resistance mechanisms and testing novel sensitizing agents.

How are these cell lines authenticated and maintained?

All cell lines undergo rigorous quality control, including morphological assessment and growth curve analysis. They are cryopreserved at early passages to ensure genetic stability and consistency across experiments.

What is the significance of the different HeLa derivatives?

The HeLa derivatives, such as HeLa S3, hela S3/DDP (cisplatin-resistant), and MR1-3 (MNNG-resistant), provide researchers with models that exhibit specific resistance phenotypes or altered growth behaviors, making them invaluable for comparative studies and therapeutic development.

Do you provide detailed characterization data for each cell line?

Yes, each cell line comes with detailed documentation, including origin, morphology, and key biological features. Additional characterization data, such as receptor status or resistance markers, are available upon inquiry to support your experimental design.

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Species

  • Cat (1)
  • Human (989)
  • Mouse (5)
  • Rat (1)

Source

  • Abdomen Metastasis (2)
  • Adrenal Gland (7)
  • Adrenal Gland Metastasis (2)
  • Ascites (23)
  • Ascites Metastasis (32)
  • Bile Duct (3)
  • Bladder (12)
  • Blood (120)
  • Bone (21)
  • Bone Marrow (43)
  • Bone Marrow Metastasis (18)
  • Bone Metastasis (6)
  • Brain (31)
  • Brain Metastasis (6)
  • Breast (8)
  • Bronchus (1)
  • Cecum (3)
  • Cerebrospinal Fluid (1)
  • Cerebrospinal Fluid Metastasis (1)
  • Cervix (32)
  • Colon (83)
  • Cornea (3)
  • Cutaneous Metastasis (1)
  • Dermis (1)
  • Duodenum (1)
  • Endometrium (17)
  • Esophagus (44)
  • Eye (12)
  • Eye Socket (5)
  • Fetus (1)
  • Foreskin (4)
  • Gallbladder (1)
  • Gingiva (2)
  • Globe (2)
  • Groin (1)
  • Hypodermis Metastasis (5)
  • Intestine (84)
  • kidney (1)
  • Kidney (9)
  • Liver (13)
  • Liver Metastasis (17)
  • Lung (42)
  • Lung Metastasis (8)
  • Lymph Node (5)
  • Lymph Node Metastasis (56)
  • Muscle (4)
  • Muscle Metastasis (2)
  • Nose (2)
  • Omentum Metastasis (2)
  • Oral Cavity (10)
  • Ovary (13)
  • Ovary Metastasis (2)
  • Pancreas (10)
  • Pelvic Wall Metastasis (1)
  • Pelvis (1)
  • Perianal Space Metastasis (1)
  • Pericardial Effusion (1)
  • Pericardial Effusion Metastasis (1)
  • Perineus (1)
  • Peripheral Blood (119)
  • Peritoneal Effusion (2)
  • Peritoneum (1)
  • Peritoneum Metastasis (1)
  • Pharynx (3)
  • Pleural Effusion (54)
  • Pleural Effusion Metastasis (44)
  • Prostate (4)
  • Rectum (13)
  • Renal Pelvis (1)
  • Retroperitoneal Space (2)
  • Salivary Gland (2)
  • Skeletal Muscle (1)
  • Skin (22)
  • Skin Metastasis (3)
  • Small Intestine (1)
  • Small Intestine Metastasis (1)
  • Soft Tissue Metastasis (1)
  • Stomach (4)
  • Testis (9)
  • Thoracic Cavity Metastasis (6)
  • Thyroid Gland (15)
  • Thyroid Gland Metastasis (1)
  • Tongue (5)
  • Umbilical Cord (1)
  • Umbilical Cord Blood (1)
  • Urachus (1)
  • Ureter (1)
  • Uterus (53)
  • Uvea (2)
  • Vagina (2)
  • Vulva (1)

Disease

  • Acute Biphenotypic Leukemia (1)
  • Acute Erythroid Leukemia (4)
  • Acute Megakaryoblastic Leukemia (4)
  • Acute Monocytic Leukemia (9)
  • Acute Myeloid Leukemia (25)
  • Acute Promyelocytic Leukemia (2)
  • Adrenal Gland Neuroblastoma (11)
  • Adult B Acute Lymphoblastic leukemia (1)
  • Adult B Acute Lymphoblastic Leukemia (6)
  • Adult T Acute Lymphoblastic Leukemia (6)
  • Adult T Lymphoblastic Lymphoma (2)
  • Adult T-Cell Leukemia/Lymphoma (1)
  • Alveolar Rhabdomyosarcoma (4)
  • Alveolar Ridge Squamous Cell Carcinoma (1)
  • Amelanotic Melanoma (3)
  • Ampulla of Vater Adenocarcinoma (1)
  • Ampulla of Vater Adenosquamous Carcinoma (3)
  • Anaplastic Astrocytoma (3)
  • Anaplastic Large Cell Lymphoma (7)
  • Askin Tumor (1)
  • Astrocytoma (5)
  • B Acute Lymphoblastic Leukemia (2)
  • B-Cell Non-Hodgkin Lymphoma (5)
  • Bare Lymphocyte Syndrome Type 2 (1)
  • Barrett Adenocarcinoma (2)
  • Benign Prostatic Hyperplasia (1)
  • Bladder Carcinoma (12)
  • Bladder Squamous Cell Carcinoma (1)
  • Breast Adenocarcinoma (1)
  • Breast Carcinoma (9)
  • Breast Ductal Carcinoma (2)
  • Burkitt Lymphoma (17)
  • Canavan Disease (1)
  • Cecum Adenocarcinoma (3)
  • Central Nervous System Lymphoma (2)
  • Cervical Adenocarcinoma (2)
  • Cervical Adenosquamous Carcinoma (2)
  • Cervical Small Cell Carcinoma (1)
  • Cervical Squamous Cell Carcinoma (2)
  • Childhood B Acute Lymphoblastic Leukemia (13)
  • Childhood T Acute Lymphoblastic Leukemia (16)
  • Childhood T Lymphoblastic Lymphoma (1)
  • Cholangiocarcinoma (2)
  • Chronic Eosinophilic Leukemia (1)
  • Chronic Lymphocytic Leukemia (2)
  • Chronic Myeloid Leukemia (23)
  • Clear Cell Renal Cell Carcinoma (2)
  • Colon Adenocarcinoma (53)
  • Colon Carcinoma (33)
  • Colorectal Adenocarcinoma (1)
  • Colorectal Carcinoma (1)
  • Congenital Pure Red Cell Aplasia (1)
  • Cutaneous Melanoma (10)
  • Dedifferentiated Chondrosarcoma (1)
  • Desmoplastic Melanoma (1)
  • Diffuse Large B-Cell Lymphoma (28)
  • Down Syndrome (2)
  • EBV-Related Burkitt Lymphoma (12)
  • Embryonal Carcinoma (3)
  • Embryonal Rhabdomyosarcoma (3)
  • Endometrial Adenocarcinoma (13)
  • Endometrial Adenosquamous Carcinoma (2)
  • Endometrial Carcinoma (2)
  • Endometrioid Stromal Sarcoma (1)
  • Epithelioid Hemangioendothelioma (1)
  • Epithelioid Sarcoma (3)
  • Esophageal Adenocarcinoma (6)
  • Esophageal Squamous Cell Carcinoma (41)
  • Essential Thrombocythemia (1)
  • Ewing Sarcoma (2)
  • Extraskeletal Myxoid Chondrosarcoma (1)
  • Fanconi Anemia (1)
  • Fibrosarcoma (1)
  • Follicular Lymphoma (2)
  • Gallbladder Carcinoma (2)
  • Gallbladder Undifferentiated Carcinoma (2)
  • Gastric Adenocarcinoma (6)
  • Gastric Adenosquamous Carcinoma (1)
  • Gastric Carcinoma (5)
  • Gastric Choriocarcinoma (1)
  • Gastric Fundus Carcinoma (1)
  • Gastric Signet Ring Cell Adenocarcinoma (1)
  • Gastric Small Cell Carcinoma (2)
  • Gastric Tubular Adenocarcinoma (5)
  • Gastroesophageal Junction Adenocarcinoma (1)
  • Gestational Choriocarcinoma (1)
  • Gingival Squamous Cell Carcinoma (2)
  • Glioblastoma (18)
  • Gliosarcoma (1)
  • Hairy Cell Leukemia (1)
  • Hepatoblastoma (2)
  • Hepatocellular Carcinoma (6)
  • Hepatosplenic T-Cell Lymphoma (2)
  • Hereditary Thyroid Gland Medullary Carcinoma (1)
  • High Grade B-Cell Lymphoma (1)
  • High Grade Ovarian Serous Adenocarcinoma (8)
  • Hodgkin Lymphoma (9)
  • Hypopharyngeal Squamous Cell Carcinoma (2)
  • Infectious Mononucleosis (1)
  • Intrahepatic Cholangiocarcinoma (6)
  • Invasive Breast Carcinoma of No Special Type (12)
  • Kidney Neoplasm (1)
  • Kidney Rhabdoid Tumor (1)
  • Krukenberg Tumor (1)
  • Liposarcoma (1)
  • Lung Adenocarcinoma (17)
  • Lung Giant Cell Carcinoma (8)
  • Lung Large Cell Carcinoma (9)
  • Lung Mucoepidermoid Carcinoma (1)
  • Lung Non-Small Cell Carcinoma (2)
  • Lung Small Cell Carcinoma (25)
  • Lung Squamous Cell Carcinoma (9)
  • Lymphoblastic Lymphoma (1)
  • Malignant Peripheral Nerve Sheath Tumor (1)
  • Mantle Cell Lymphoma (5)
  • Mature Gastric Teratoma (1)
  • Maxillary Sinus Squamous Cell Carcinoma (1)
  • Medulloblastoma (3)
  • Melanoma (24)
  • Meningioma (2)
  • Minimally Invasive Lung Adenocarcinoma (1)
  • Monophasic Synovial Sarcoma (1)
  • Mouse Intestinal Tract Neuroendocrine Adenoma (1)
  • Mouse Mammary Gland Malignant Neoplasm (2)
  • Mouse Plasmacytoma (1)
  • Mycosis Fungoides (1)
  • Myelodysplastic Syndrome (1)
  • Myxofibrosarcoma (1)
  • Natural Killer Cell Lymphoblastic Leukemia/Lymphoma (2)
  • Neuroblastoma (26)
  • Oral Cavity Squamous Cell Carcinoma (15)
  • Osteoid Osteoma (1)
  • Osteosarcoma (15)
  • Ovarian Carcinoma (1)
  • Ovarian Clear Cell Adenocarcinoma (1)
  • Ovarian Endometrioid Adenocarcinoma (4)
  • Ovarian Granulosa Cell Tumor (1)
  • Ovarian Mucinous Adenocarcinoma (2)
  • Ovarian Serous Adenocarcinoma (2)
  • Ovarian Serous Cystadenocarcinoma (2)
  • Ovarian Small Cell Carcinoma (1)
  • Pancreatic Adenocarcinoma (13)
  • Pancreatic Carcinoma (5)
  • Pancreatic Ductal Adenocarcinoma (12)
  • Papillomavirus-Independent Cervical Squamous Cell Carcinoma (1)
  • Papillomavirus-Related Cervical Adenocarcinoma (7)
  • Papillomavirus-Related Cervical Squamous Cell Carcinoma (4)
  • Papillomavirus-Related Endocervical Adenocarcinoma (16)
  • Paroxysmal Nocturnal Hemoglobinuria (3)
  • Pharyngeal Squamous Cell Carcinoma (1)
  • Plasma Cell Myeloma (15)
  • Pleural Epithelioid Mesothelioma (5)
  • Pleural Sarcomatoid Mesothelioma (2)
  • Poorly Differentiated Thyroid Gland Carcinoma (1)
  • Primary Cutaneous T-Cell Non-Hodgkin Lymphoma (1)
  • Primary Effusion Lymphoma (7)
  • Primitive Neuroectodermal Tumor (1)
  • Prostate carcinoma (1)
  • Prostate Carcinoma (9)
  • Rectal Adenocarcinoma (13)
  • Rectosigmoid Adenocarcinoma (1)
  • Recurrent Bladder Carcinoma (1)
  • Renal Cell Carcinoma (7)
  • Renal Pelvis Urothelial Carcinoma (1)
  • Retinoblastoma (11)
  • Sacral Chordoma (1)
  • Sacrococcygeal Teratoma (1)
  • Salivary Gland Squamous Cell Carcinoma (1)
  • Sezary Syndrome (1)
  • Shwachman-Diamond Syndrome (1)
  • Skin Squamous Cell Carcinoma (2)
  • Splenic Marginal Zone Lymphoma (1)
  • Testicular Embryonal Carcinoma (8)
  • Testicular Teratoma (2)
  • Testicular Yolk Sac Tumor (1)
  • Thyroid Gland Anaplastic Carcinoma (10)
  • Thyroid Gland Follicular Carcinoma (4)
  • Thyroid Gland Papillary Carcinoma (3)
  • Thyroid Gland Sarcoma (1)
  • Thyroid Gland Squamous Cell Carcinoma (2)
  • Tongue Adenosquamous Carcinoma (1)
  • Tongue Squamous Cell Carcinoma (6)
  • Type I Endometrial Adenocarcinoma (1)
  • Ureter Urothelial Carcinoma (1)
  • Uterine Carcinosarcoma (2)
  • Uterine Corpus Leiomyosarcoma (1)
  • Uterine Corpus Sarcoma (2)
  • Uveal Melanoma (2)
  • Vaginal Melanoma (2)
  • Vulvar Melanoma (1)
  • Vulvar Squamous Cell Carcinoma (1)

Description: Species: human, Caucasian female; Tissue: umbilical cord

Cat#: CSC-6260W INQUIRY

Description: The HeLa 382 cell line is a subclone of the cell line HeLa. The original HeLa cell line was derived ...

Cat#: CSC-6261W INQUIRY

Description: The HeLa 422 cell line is a subclone of the cell line HeLa. The original HeLa cell line was derived ...

Cat#: CSC-6262W INQUIRY

Description: Transfected with the exon 4 defective variant of ER-pBact cDNA, human estrogen receptor cDNA, under ...

Cat#: CSC-6263W INQUIRY

Description: These cells were cloned from the GIRARDI HEART cell line (passage #623) in 1981 and were thought to ...

Cat#: CSC-C0283 INQUIRY

Description: These cells were cloned from the GIRARDI HEART cell line (passage #623) in 1981 and were thought to ...

Cat#: CSC-C0285 INQUIRY

Description: Established from the ascitic fluid of a 69-year-old Caucasian woman with endometrial carcinoma in ...

Cat#: CSC-C0337 INQUIRY

Description: Established from the surgically removed, chemotherapy-resistant cervix adenocarcinoma of a ...

Cat#: CSC-C0393 INQUIRY

Description: Established from tumor tissue from a 77-year-old woman with recurrence of endometrial carcinoma ...

Cat#: CSC-C0454 INQUIRY

Description: Established from the transitional cell carcinoma (small, grade III) removed from the left ureter of ...

Cat#: CSC-C0456 INQUIRY

Description: Established from the primary tumor of a 68-year-old Caucasian woman with moderately differentiated ...

Cat#: CSC-C0459 INQUIRY

Description: Established from the primary adenosquamous endometrium carcinoma (grading G1-G2) of an 81-year-old ...

Cat#: CSC-C0462 INQUIRY

Description: established from the endometrium of a 39-year-old female with type I endometrial adenocarcinoma

Cat#: CSC-C30041J INQUIRY

Description: Expressing receptor to estrogen and progesterone. Cell growth is slow.

Cat#: CSC-C4621J INQUIRY

Description: The parental continuous cell line HELA was established from the primary cervix carinoma of a ...

Cat#: CSC-C6211X INQUIRY

Description: KB-V1 is a multidrug-resistant (mdr) subclone derived in 1985 from KB-3-1 which itself is a ...

Cat#: CSC-C6212X INQUIRY

Description: Human cell line derived from melanotic melanoma (highly melanotic).

Cat#: CSC-C6251J INQUIRY

Description: Human cell line derived from uterine cervical epidermoid carcinoma.

Cat#: CSC-C6341J INQUIRY

For research use only. Not for any other purpose.