Gastrointestinal Cells
Our gastrointestinal cell portfolio includes primary human cell models derived from the stomach, small intestine, colon, rectum, and associated vascular and mesenteric tissues. These biologically relevant cells support research in gastrointestinal physiology, epithelial barrier function, intestinal inflammation, mucosal repair, motility disorders, angiogenesis, and gastrointestinal oncology.
The collection encompasses epithelial cells, fibroblasts, smooth muscle cells, microvascular endothelial cells, and tumor-associated vascular models, enabling researchers to investigate complex cellular interactions across the gastrointestinal microenvironment and disease-specific pathways.
Our Gastrointestinal Cell Portfolio Highlights
Comprehensive Gastrointestinal Cell Resources
Our portfolio represents the major cellular compartments of the gastrointestinal tract, supporting studies from basic tissue biology to disease modeling.
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Multi-Region Gastrointestinal Models
- Stomach, small intestine, colon, and rectum-derived cell types
- Region-specific epithelial, stromal, and vascular models
- Suitable for comparative gastrointestinal studies
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Complete Tissue Microenvironment Coverage
- Epithelial cells, fibroblasts, and smooth muscle cells
- Microvascular and mesenteric endothelial cell populations
- Models supporting multicellular gastrointestinal systems
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Disease-Relevant Cell Resources
- Colon carcinoma epithelial cells
- Tumor-associated endothelial cells
- Models for gastrointestinal cancer and vascular biology research
Gastrointestinal Research Support
We support investigations into digestive tract physiology, barrier integrity, tissue remodeling, vascular function, and gastrointestinal disease mechanisms.
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Barrier Function and Mucosal Biology
Suitable for evaluating epithelial integrity, permeability, nutrient transport, host-environment interactions, and mucosal responses to injury.
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Fibrosis and Tissue Remodeling Studies
Support for investigations involving fibroblast activation, extracellular matrix regulation, wound repair, and chronic inflammatory remodeling.
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Motility and Smooth Muscle Research
Applicable for studying gastrointestinal contractility, smooth muscle physiology, and mechanisms underlying motility disorders.
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Vascular and Tumor Microenvironment Applications
Useful for examining angiogenesis, endothelial function, tumor-associated vasculature, and stromal interactions within gastrointestinal cancers.
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Digestive Tract
Regions Represented
4
Major Cell
Compartments
20+
Primary Gastrointestinal
Cell Models
Which gastrointestinal cell types are most suitable for intestinal barrier studies?
Human intestinal epithelial cells, small intestinal epithelial cells, and stomach epithelial cells are commonly used to investigate epithelial integrity, permeability, nutrient transport, and mucosal responses to environmental or inflammatory stimuli.
How can researchers model the gastrointestinal microenvironment in vitro?
Combining epithelial cells with fibroblasts, smooth muscle cells, and microvascular endothelial cells enables the development of more physiologically relevant co-culture systems that better reflect tissue architecture and cell-cell interactions.
What cell models are commonly used to study intestinal fibrosis and tissue remodeling?
Intestinal fibroblasts, colonic fibroblasts, and mesenteric fibroblasts are valuable tools for investigating extracellular matrix deposition, fibroblast activation, wound healing, and chronic inflammatory remodeling processes.
Can these cells support gastrointestinal motility research?
Yes. Gastrointestinal smooth muscle cells derived from the stomach, intestine, and rectum are widely used to evaluate contractile activity, smooth muscle signaling pathways, and mechanisms associated with motility disorders.
What is the value of tumor-associated endothelial cells in gastrointestinal cancer studies?
Colon tumor-associated endothelial cells provide a relevant model for studying tumor angiogenesis, vascular remodeling, endothelial-cancer cell interactions, and the development of anti-angiogenic therapeutic strategies.
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Species
- Human (797)
- Mouse (3)
- Rat (1)
Source
- Adipose (9)
- Adrenal Gland (4)
- Airway (7)
- Aorta (16)
- Artery (47)
- Bile Duct (1)
- Bladder (8)
- Blood (157)
- Bone (3)
- Bone Marrow (81)
- Brain (36)
- Breast (10)
- Bronchus (20)
- Cartilage (6)
- Chorion (2)
- Choroid (3)
- Ciliary Body (1)
- Colon (10)
- Conjunctiva (2)
- Cord Blood (24)
- Cornea (2)
- Dental Pulp (4)
- Dermis (43)
- Embryo (2)
- Endometrium (2)
- Epidermis (19)
- Esophagus (4)
- Eye (20)
- Foreskin (2)
- Gallbladder (1)
- Gingiva (2)
- Hair Follicle (5)
- Heart (14)
- Intestine (20)
- Iris (1)
- Kidney (31)
- Lens (1)
- Liver (34)
- Lung (56)
- Lymph Node (2)
- Mesentery (3)
- Nose (1)
- Oral Cavity (3)
- Ovary (10)
- Pancreas (8)
- Pancreatic Islet (1)
- Perineurium (1)
- Periodontal Ligament (2)
- Periodontium (4)
- Peripheral Blood (130)
- Peritoneal Cavity (2)
- Placenta (11)
- Prostate (8)
- Rectum (1)
- Retina (9)
- Seminal Vesicle (1)
- Skeletal Muscle (9)
- Skin (78)
- Small Intestine (5)
- Spinal Cord (1)
- Spleen (6)
- Stomach (3)
- Synovial Fluid (2)
- Synovium (8)
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- Thyroid (4)
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- Trabecular Meshwork (1)
- Trachea (6)
- Umbilical Cord (23)
- Uterus (7)
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- Vein (30)
Cell Type
- Astrocyte (9)
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- CD133+ Cell (6)
- CD34+ Cell (16)
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- Dendritic Cell (4)
- Endothelial Cell (133)
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- Epithelial Cell (84)
- Fibroblast (139)
- Glial Cell (14)
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- Microvascular Cell (61)
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- NK Cell (5)
- Oligodendrocyte Progenitor Cell (3)
- Osteoblast (3)
- Pancreatic Stellate Cell (1)
- Pericyte (10)
- Podocyte (1)
- Preadipocyte (10)
- Progenitor Cell (4)
- Red Blood Cell (1)
- Satellite Cell (1)
- Schwann Cell (1)
- Sebocyte (1)
- Sertoli Cell (1)
- Skeletal Muscle Cell (2)
- Smooth Muscle Cell (48)
- Stromal Cell (16)
- Synoviocyte (6)
- T Cell (28)
- Tenocyte (1)
- Trabecular Meshwork Cell (1)
- Trophoblast (1)
Disease
- Acute Lymphocytic Leukemia (ALL) (15)
- Acute Myeloid Leukemia (AML) (13)
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- Aplastic Anemia (AA) (1)
- Arteriovenous Malformation (AVM) (1)
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- Astrocytoma (2)
- Autoimmune Hemolytic Anemia (AIHA) (1)
- Autoimmune Lymphoproliferative Syndrome (ALPS) (1)
- Breast Cancer (3)
- Cancer (121)
- Chronic Lymphocytic Leukemia (CLL) (19)
- Chronic Myeloid Leukemia (CML) (14)
- Chronic Obstructive Pulmonary Disease (COPD) (6)
- Colon Cancer (4)
- Crohn's Disease (3)
- Cystic Fibrosis (CF) (7)
- Diabetes (35)
- Diabetes Type 1 (16)
- Diabetes Type 2 (18)
- Diffuse Large B-Cell Lymphoma (4)
- Dilated Cardiomyopathy (DCM) (1)
- Duchenne Muscular Dystrophy (DMD) (5)
- Essential Thrombocythemia (ET) (1)
- Glioblastoma (3)
- Guillain-Barre Syndrome (GBS) (1)
- Hypertension (27)
- Idiopathic Thrombocytopenic Purpura (ITP) (1)
- Inflammatory Bowel Disease (IBD) (5)
- Iron-Deficiency Anemia (1)
- Kidney Cancer (3)
- Legg–Calvé–Perthes Disease (LCPD) (2)
- Leukopenia (1)
- Liver Cancer (3)
- Lung Cancer (6)
- Mantle Cell Lymphoma (MCL) (8)
- Melanoma (2)
- Mucopolysaccharidosis (2)
- Multiple Myeloma (MM) (12)
- Multiple Sclerosis (MS) (3)
- Muscular Dystrophy (MD) (1)
- Myelodysplastic Syndrome (MDS) (3)
- Neurofibromatosis (NF) (3)
- Non-Hodgkin Lymphoma (NHL) (10)
- Normal (524)
- Osteoarthritis (OA) (5)
- Ovarian Cancer (6)
- Pancreatic Cancer (1)
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- Parkinson's Disease (PD) (2)
- Plasmacytoma (1)
- Polycythemia (1)
- Prostate Cancer (3)
- Psoriasis (4)
- Rheumatoid Arthritis (RA) (7)
- Robertsonian Translocation (ROB) (1)
- Sickle Cell Anemia (2)
- Systemic Lupus Erythematosus (SLE) (4)
- Thrombocytopenia (1)
- Transverse Myelitis (TM) (1)
- Ulcerative Colitis (UC) (2)
- Waldenström Macroglobulinemia (WM) (2)
Description: Smooth muscle contraction is the fundamental event in gastrointestinal motion. Inflammation of the ...
Description: Smooth muscle contraction is the fundamental event in gastrointestinal motion. Although many of the ...
Description: Endothelial cells lining the microvasculature are known to play a critical "gatekeeper" role in the ...
Description: Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively ...
Description: Smooth muscle is responsible for the contractility of hollow organs, such as blood vessels, the ...
Description: Human Primary Colonic Fibroblast are isolated from normal human colon tissue. Human Primary Colonic ...
Description: Human Primary Intestinal Vascular Fibroblasts from Creative Bioarray are isolated from normal human ...
Description: The colorectum is a major organ for both malignant and nonmalignant diseases. Cells that line the ...
Description: Primary Human Intestinal Microvascular Endothelial Cells were initiated by elutriation from ...
Description: Primary Human Large Intestine Microvascular Endothelial Cells were initiated from normal human ...
Description: Human Intestinal Vascular Fibroblasts are isolated from normal human intestinal tissue.
Description: Human Intestinal Fibroblasts are isolated from normal human intestine tissue.
Description: Human Small Intestinal Smooth Muscle Cells are isolated from human small intestine tissue.
Description: Human Stomach Smooth Muscle Cells are isolated from human stomach tissue.
Description: Human Colonic Tumor-Associated Endothelial Cells from Creative Bioarray are isolated from human ...
Description: Human Intestinal Mesenteric Vascular Endothelial Cells from Creative Bioarray are isolated from ...
Description: Human Colonic Microvascular Endothelial Cells from Creative Bioarray are isolated from human colon ...
Description: Human Small Intestinal Microvascular Endothelial Cells from Creative Bioarray are isolated from ...