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Optical in vivo imaging is unequivocally the most versatile and widely used visualization modality in clinical practice and research. It has now been applied in animal models of cancer, stem cell research, siRNA research and drug metabolism. The benefits of this technique are that it gives the most complete picture of the biological effects of a treatment or disease progression. Besides, the animal is kept alive allowing future analysis on the same subject. The major technologies applied to in vivo imaging are bioluminescence and fluorescence.
Luciferin and coelenterazine are common bioluminescent reporters used for in vivo imaging. Their common mechanism of action is that under the catalysis of ATP and luciferase, the substrate is oxidized and luminescence.
Cyanine and Fluor dyes are excellent fluorescent dyes for labeling and detection of proteins, antibodies, nucleic acids and other biomolecules. They are the longest wavelength dyes with the highest fluorescence intensity and stability. They are especially suitable for in vivo imaging instead of radioactive elements.
Creative Bioarray provides a large number of luciferase products and fluorescent dyes, which are the most trusted products available. Our team is always committed to providing customers with high quality products and services. Please contact us at firstname.lastname@example.org or 1-631-626-9181.