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ActoFactor™ Recombinant Mouse Interleukin 10

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0688
  • Description
  • Recombinant Murine Interleukin-10 (rMu IL-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 18.7 kDa protein of 161 amino acid residues that shares over 80% sequence homology with the Epstein-Barr Virus protein BCRFI. The reported biological activities of IL-10, which may be inter-related, include inhibition of macrophage mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the TH2 cell response, which results in elevated antibody production.
  • Species
  • Mouse
  • Product Overview
  • Mouse Il10 expressed in E.coli
  • Molecular Mass
  • 18.7 kDa
  • Size
  • CAT# CSC-CTK0688-10 (10 μg); CAT# CSC-CTK0688-50 (50 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 98% as determined by SDS-PAGE and HPLC analysis.
  • Activity
  • The ED50 as determined by the dose-dependent co-stimulation (with IL-4) of the proliferation of murine MC/9 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of Greater than 5 x 10^5 units/mg.
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • Lyophilized from a sterile-filtered protein solution with no additives.
  • Reconstitution
  • Please centrifuge product briefly before opening the vial. The lyophilized rMu IL-10 should be reconstituted in sterile, ultrapure water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • The lyophilized powder, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted rMu IL-10 should be used immediately or stored long-term in undiluted working aliquots at -20°C. Avoid repeated freeze / thaw cycles.

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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
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      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com