Molecular Karyotyping (aCGH) Service
Array Comparative Genomic Hybridization (aCGH) is a high resolution karyotype analysis solution for the detection of unbalanced structural and numerical chromosomal alterations with high-throughput capabilities. Addition of SNPs can also detect polylpoidy, loss of heterozygosity, and uniparental disomy. This method has significantly high resolution, which overcomes the limitation of traditional karyotyping (G-banded) as even high resolution karytoypes are unreliable for detection of many known microdeletion syndromes which range from 3-5 Mb in size.
Creative Bioarray offers a wide range of Karyotyping Services (Traditional Karyotyping-G Banded, M-FISH, Molecular Karyotyping, etc) to meet your different needs. Creative Bioarray can provide you with the best research support in karyotyping analysis field.
Work Flow
Applications
- Detect chromosomal aberrations in tumor cells: aneuploidies, deletions, duplications, and/or amplifications of any locus represented on the array
- Monitorthe progression of tumors
- Detect submicroscopic aberrations
Features
- High resolution
- High accuracy and sensitivity
- Competitive prices
- Fast turnaround time
Quotations and ordering
Our customer service representatives are available 24hr a day! We thank you for choosing Creative Bioarray at your preferred Karyotyping Services.
References
- Albertson D G.:, et al. Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene[J]. Nature genetics, 2000, 25(2): 144.
- Hupé P.:, et al. Analysis of array CGH data: from signal ratio to gain and loss of DNA regions[J]. Bioinformatics, 2004, 20(18): 3413-3422.
- Hodgson G, Hager J H.:, et al. Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas[J]. Nature genetics, 2001, 29(4): 459.
- Iafrate A J.:, et al. Detection of large-scale variation in the human genome[J]. Nature genetics, 2004, 36(9): 949.
- Park H.:, et al. Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing[J]. Nature genetics, 2010, 42(5): 400-405.