Online Inquiry & Support

USA: 1-631-626-9181   Fax: 1-631-614-7828
Europe: 44-207-097-1828
Email: info@creative-bioarray.com

ActoFactor™ Recombinant Human Resistin-like Molecule beta

Bookmark and Share
  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0506
  • Description
  • RELM-beta is a member of a recently identified family of secreted proteins containing a conserved cystein-rich C-terminus. The RELM family consists of resistin (also called FIZZ3), RELM-alpha (FIZZ1), RELM-beta (FIZZ2) and RELM-gamma. While all four RELM family members were identified in rodents, only resisistin and RELM-beta were found in humans. RELM-beta appears to be produced as a homodimer exclusively by intestinal goblet cells and can be found in high quantities in stool. Remarkably, stool of germ-free mice displaying a sterile intestinal tract does not contain RELM-beta until bacterial colonization starts after pathogen-free mice have entered the natural environment. Some, but not all, colon carcinoma cell lines secrete RELM-beta into the cell culture supernatant. The physiological function of RELM-beta is not known. High doses of recombinant RELM-beta showed hyperglycemic effects including lowered glucose disposal and increased hepatic glucose production in mice. Recombinant human RELM- beta is a His-tagged fusion protein of 11 kDa protein containing 90 amino acid residues of the human RELM-beta and 12 additional amino acid residues including the 6xHis-tag.
  • Species
  • Human
  • Product Overview
  • Human RETN expressed in E.coli
  • Molecular Mass
  • 11 kDa
  • Size
  • CAT# CSC-CTK0506-25 (25 μg); CAT# CSC-CTK0506-125 (125 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 95% as determined by SDS-PAGE analysis.
  • Activity
  • N/A
  • Endotoxin Level
  • N/A
  • Formulation
  • Sterile-filtered, white, lyophilized (freeze-dried) powder. Sterile-filtered and lyophilized from 0.5 mg/ml solution in 0.05 M acetate buffer (pH 4).
  • Reconstitution
  • Please centrifuge product briefly before opening vial. For reconstitution, add 0.2 ml of 0.1 M acetate buffer (pH 4) and let the lyophilized pellet dissolve completely. For conversion into a higher pH value, we recommend intensive dilution by the relevant buffer to a concentration of 10 μg/ml. In higher concentrations the solubility of this antigen is limited. This solution can then be stored at -20°C for future use.
  • Storage & Stability
  • The lyophilized protein is best stored desiccated at -20°C. Reconstituted rRELM beta should be used immediately or stored long-term in undiluted working aliquots at -20°C. Avoid repeated freeze-thaw cycles.

Citation Guidance:
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.

Price Inquiry

Please input "bioarray" as verification code.

SEARCH

tissue samples, tissue arrays, cells, microorganisms, probes and services for your research.

  

SEARCH

Contact Us
    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
Ordering Information
    • Payment methods we support:
      ✭ Invoice / Purchase Order
      ✭ Credit card
Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com