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ActoFactor™ Recombinant Human Interferon regulatory factor 4

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0186
  • Description
  • IRF-4 is a transcriptional activator, belonging to the IRF family. It binds to the interferon- stimulated response element (ISRE) of the MHC Class I promoter (but is not induced by Interferons). IRF-4 binds the immunoglobulin lambda light chain enhancer, together with Pu.1. It most likely plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. IRF-4 / MUM-1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B cells mainly located in the "light zone". Its morphologic spectrum ranged from that of centrocyte to that of a plasmablast/plasma cell, and it displayed a phenotype (MUM-1+/Bcl-6/Ki67 ) different from that of most GC B cells (MUM-1 /Bcl-6+/Ki67+) and mantle B cells (MUM-1 /Bcl-6 /Ki67). Human recombinant IRF-4 (aa 144-451) expressed in E. coli is fused to a GST-tag and purified by proprietary chromatographic techniques.
  • Species
  • Human
  • Product Overview
  • Human IRF4 expressed in E.coli
  • Molecular Mass
  • N/A
  • Size
  • CAT# CSC-CTK0186-2 2 μg; CAT# CSC-CTK0186-10 (10 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 90% as determined by SDS-PAGE analysis.
  • Activity
  • N/A
  • Endotoxin Level
  • N/A
  • Formulation
  • Sterile-filtered, colorless protein solution in 50 mM Tris-Acetate (pH 7.5), 1 mM EDTA and 20% glycerol.
  • Reconstitution
  • Please centrifuge product briefly before opening vial. The dissolved protein can be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • Store frozen at -20°C. Avoid multiple freeze-thaw cycles.

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    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
Ordering Information
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com