Online Inquiry & Support

USA: 1-631-626-9181   Fax: 1-631-614-7828
Europe: 44-207-097-1828
Email: info@creative-bioarray.com

ActoFactor™ Recombinant Human Insulin-like growth factor 2 (somatomedin A)

Bookmark and Share
  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0057
  • Description
  • Insulin-like growth factor II (IGF-2) and IGF-I are family members of insulin-like growth factors that are structurally homologous to proinsulin, and share approximately 70% sequence identity. IGF-2 is expressed in many tissues and autocrine, paracrine and endocrine functions have been reported. Mature IGF-2 is highly conserved and has cross-species reactivity. Two specific cell surface receptors, type I IGF and type II IGF receptors, that bind IGF-1 and IGF-2 have been identified. Recombinant human IGF-2 contains 67 amino acids and has a predicted molecular mass of approximately 7.5 kDa.
  • Species
  • Human
  • Product Overview
  • Human IGF2 expressed in E.coli
  • Sequence
  • A DNA sequence encoding the mature IGF-2 protein was expressed in E. coli.
  • Size
  • CAT# CSC-CTK0057-50 (50 μg); CAT# CSC-CTK0057-250 (250 μg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 97% as determined by SDS-PAGE and visualized by silver stain
  • Activity
  • Activity was determined in a serum-free cell proliferation assay using the human cell line MCF-7 and the ED50 for this effect was typically 5.0 - 10.0 ng/mL.
  • Endotoxin Level
  • Endotoxin level less than 0.1 ng per 1 mg of the cytokine as determined by the LAL method.
  • Formulation
  • Lyophilized from a 0.2 μm filtered solution in 0.1 M acetic acid.
  • Reconstitution
  • It is recommended that PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 mg/mL of the cytokine.
  • Storage & Stability
  • Lyophilized samples are stable for greater than six months at -20°C to -70°C. Reconstituted hIGF-2 can be stored under sterile conditions at 2°C to 4°C for one month or at -20°C to -70°C for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Citation Guidance:
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.

Price Inquiry

Please input "bioarray" as verification code.

SEARCH

tissue samples, tissue arrays, cells, microorganisms, probes and services for your research.

  

SEARCH

Contact Us
    • USA
      45-1 Ramsey Road, Shirley, NY 11967, USA
      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
      Europe
      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
Ordering Information
    • Payment methods we support:
      ✭ Invoice / Purchase Order
      ✭ Credit card
Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com