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ActoFactor™ Recombinant Human Glucagon-Like Peptide 1

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  • Specification
  • Recommended Products
  • Cat.No.
  • CSC-CTK0636
  • Description
  • GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP- 1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin- related pancreatic peptide (GRPP), glucagons, and GLP-2. Recombinant human GLP-1 is a 3.3 kDa consisting of 31 amino acid residues.
  • Species
  • Human
  • Product Overview
  • Human GCG expressed in E.coli
  • Molecular Mass
  • 3.3 kDa
  • Size
  • CAT# CSC-CTK0636-1 (1 mg); CAT# CSC-CTK0636-5 (5 mg)
  • Expression System
  • E.coli
  • Purity
  • Greater than 95% as determined by SDS-PAGE and HPLC analysis.
  • Activity
  • N/A
  • Endotoxin Level
  • Less than 1 EU/μg.
  • Formulation
  • Sterile filtered through a 0.2 micron filter and lyophilized with no additives.
  • Reconstitution
  • Please centrifuge product briefly before opening vial. The lyophilized protein should be reconstituted in sterile, ultra-pure water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at -20°C for future use.
  • Storage & Stability
  • The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted rHu GLP-1 should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.

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      Tel: 1-631-626-9181
      Fax: 1-631-614-7828
      Email: info@creative-bioarray.com
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      Tel: 44-207-097-1828
      Email: info@creative-bioarray.com
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Contact Us
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-bioarray.com

Europe
Tel: 44-207-097-1828
Email: info@creative-bioarray.com