Featured Products
- EUB338 Probe
- WCP 1 FISH Probe
- WCP 2 FISH Probe
- WCP 5 FISH Probe
- WCP 7 FISH Probe
- WCP 11 FISH Probe
- WCP 17 FISH Probe
- WCP Y FISH Probe
- Mouse Chromosome 2 Point Probe
- Mouse Chromosome 4 Point Probe
- Mouse Chromosome 5 Point Probe
- Mouse Chromosome 9 Point Probe
- Mouse Chromosome 11 Point Probe
- Mouse Chromosome 12 Point Probe
- Mouse Chromosome 14 Point Probe
- Mouse Chromosome 15 Point Probe
- Mouse Chromosome 16 Point Probe
- Mouse Chromosome 18 Point Probe
Our Promise to You
Guaranteed product quality, expert customer support
IGH/MAFB Translocation, Dual Fusion Probe
- Specification
- Recommended Products
Cat.No.
FHPC-067
Description
The t(14;20) translocation, present in around 2% of Multiple Myeloma cases is one of seven recurrent IGH translocations that are referred to as primary oncogenic events in Multiple Myeloma cases. These translocations result in a transcription product that dysregulates further controlling genes such as the cyclin family of cell cycle control genes which then disrupts normal cell division. As a result of the translocation the transcription of the IGH-MAFB fusion product is up-regulated which has been shown to cause overexpression of Cyclin D3 in around 7% of tumours.
Size
5 Tests, 10 Tests
Label
Red/Green
Locus
t(14;20)
Specificity
Human
Usage
For Research Use Only. Not for use in diagnostic procedures.Storage
Store at minus 20 centigrade
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the PubMed ID of your paper to get a coupon.
- Q & A
- Customer Review
Customer Support & Price Inquiry
