This cell line was derived from the peripheral blood of a 1 year old male with acute monocytic leukaemia. THP-1 cells show alpha-naphtyl butyrate esterase activity, phagocytose latex particles as well as sensitized sheep erythrocytes and have the ability to restore T-lymphocyte response to Con A. When incubating with TPA or DMSO the cells can be differentiated into macrophage-like cells.
Homo sapiens ,human
STR DNA Profile
Penta E: 11,15
Penta D: 10,12
Storage and Shipping
liquid nitrogen vapor phase
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Tracking immune-related cell responses to drug delivery microparticles in 3D dense collagen matrix
Authors: Obarzanek-Fojt M, Curdy C, Loggia N, et al.
The European Journal of Pharmaceutics and Biopharmaceutics. 2016, 107: 180-190.