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PC-12

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Cat.No.
CSC-C8902H
Description
The PC-12 cell line was derived from a transplantable rat pheochromocytoma. The cells respond reversibly to NGF by induction of a neuronal phenotype. The cells do not synthesize epinephrine. PC-12 adheres poorly to plastic and tends to grow in small clusters. Attachment is improved by using collagen coated flasks. The species was confirmed by Real-Time PCR.
Organism
Rattus norvegicus, rat
Karyotype
40 chromosomes; 38 autosomes plus XY
Source
adrenal gland
Culture Properties
floating clusters; few scattered lightly attached cells.
Morphology
small irregularly shaped cells
Quality Control
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
liquid nitrogen vapor phase
Disease
pheochromocytoma
Application
This cell line is a suitable transfection host.
Citation Guidance
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