Species: human (Homo sapiens)
Cell type: natural killer lymphoma
Origin: established from the peripheral blood of a 50-year-old man with non-Hodgkin lymphoma (large granular lymphocytic) in 1992; cells were described as having azurophilic granula and strong cytotoxic NK activity
cells growing in clumps in suspension
STR DNA Profile
Human hypotetraploid karyotype with 4% polyploidy
CD2 +, CD7 +, CD11a +, CD28 + , CD45 +, CD54 +, CD56 +, CD1 -, CD3 -, CD4 -, CD5 -, CD8 -, CD10 -, CD14 -, CD16 -, CD19 -, CD20 -, CD23 -, CD34 -, HLA-DR -
a. Natural killer related reserach
b. Tumor immunotherapy related research
c. Cell-Based assay
d. In vivo efficacy study
Mycoplasma: Fluorescence (DAPI) test: negative; Mycoplasma specific PCR: negative; Selective biochemical test: negative
Viruses: ELISA: reverse transcriptase negative; PCR: EBV +, HBV -, HCV -, HHV-8 -, HIV-1 -, HIV-2 -, HTLV-I/II -, MLV -, SMRV -
Storage and Shipping
Ship in dry ice.
Store in liquid nitrogen.
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