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MV4-11

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Cat.No.
CSC-C0248
Description
Established from a 10-year-old boy with acute monocytic leukemia (AML FAB M5) at diagnosis; cells were described to carry a t(4;11); we found that MV4-11 carries an FLT3 internal tandem duplication; patented cell line. Both granulocyte colony stimulating factor (G-CSF) and granulocyte- macrophage colony stimulating factor (GM-CSF) support the short term and long term growth of MV4-11 cells and act synergistically to stimulate growth of the cells. The cells are dependent upon GM-CSF for long term growth.
Organism
Homo sapiens (human)
STR DNA Profile
Amelogenin: X,Y
CSF1PO: 10,12
D13S317: 13
D16S539: 11,12
D5S818: 11,12
D7S820: 8,9
THO1: 8,9.3
TPOX: 8,11
vWA: 14,15
D3S1358: 16,17
D21S11: 32,32.2
D18S51: 11,17
Penta E: 7,18
Penta D: 9,10
D8S1179:13
FGA: 19,21
Karyotype
48, XY, t(4;11)(q21;q23), +8, +19
Source
Blood
Culture Properties
suspension
Morphology
Lymphoblast
Recommended Medium
RPMI-1640 medium supplemented with 2 mM L-glutamine, and 10% fetal bovine serum.
Quality Control
Fluorescence (DAPI) test: negative; Mycoplasma specific PCR: negative; Bacteria
specific PCR: negative
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 2.5 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
CSC-6249W
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CSC-6282W
CSC-6296W
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