MDA-MB-435S is a spindle shaped strain which evolved from the parent line (435) isolated in 1976 (R. Cailleau et al.) from the pleural effusion of a 31 year old female with metastatic ductal adenocarcinoma of the breast. Parental cells displayed the dispersed pattern (type II) when treated with immunofluorescent stain for tubulin. Recent findings point to a rather melanocytic origin of this cell line (Ellison 2002).
Homo sapiens ,human
STR DNA Profile
Penta E: 10,12
Penta D: 9,11
Breast; mammary gland (pleural effusion) / Skin?
Tests for mycoplasma, bacteria and fungi were negative
Storage and Shipping
liquid nitrogen vapor phase
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