This cell line was established from a pleural effusion of a 51 year old woman with metastatic breast cancer.
Tumorigenecity: Yes, in nude mice also in ALS treated BALB/c mice; forms poorly differentiated adenocarcinoma(grade III)
Isoenzyme: Me-2,1-2;PGM3,1;PGM1,1-2;ES-D,1;AK-1,1;GLO-1,2;G6PD B
Histopathology: adenocarcinoma; pleural effusion
Receptor Expression: epidermal growth factor (EGF), expressed; transforming growth factor alpha (TGF alpha), expressed
Oncogene: The cells express the WNT7B oncogene
Homo sapiens, human
STR DNA Profile
Penta E: 11
Penta D: 11,14
Mean chromosome number = 68; (P17), hypotriploid with abnormalities including breaks, secondary constrictions and fragmentations
Breast (pleural effusion)
Fluorescence (DAPI) test: negative; Mycoplasma specific PCR: negative; Bacteria specific PCR: negative
Storage and Shipping
liquid nitrogen vapor phase
This cell line is a suitable transfection host.
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