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MDA-MB-231

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Cat.No.
CSC-C8210L
Description
This cell line was established from a pleural effusion of a 51 year old woman with metastatic breast cancer.
Tumorigenecity: Yes, in nude mice also in ALS treated BALB/c mice; forms poorly differentiated adenocarcinoma(grade III)
Isoenzyme: Me-2,1-2;PGM3,1;PGM1,1-2;ES-D,1;AK-1,1;GLO-1,2;G6PD B
Histopathology: adenocarcinoma; pleural effusion
Receptor Expression: epidermal growth factor (EGF), expressed; transforming growth factor alpha (TGF alpha), expressed
Oncogene: The cells express the WNT7B oncogene
Tissue of Origin
Breast
Organism
Homo sapiens, human
STR DNA Profile
Amelogenin: X,X
CSF1PO:12,13
D13S317:13
D16S539:12
D5S818:12
D7S820:8,9
TH01:7,9.3
TPOX:8,9
vWA:15,19
D3S1358: 16
D21S11: 30,33.2
D18S51: 11,16
Penta E: 11
Penta D: 11,14
D8S1179: 13
FGA: 22,23
Karyotype
Mean chromosome number = 68; (P17), hypotriploid with abnormalities including breaks, secondary constrictions and fragmentations
Source
Breast (pleural effusion)
Culture Properties
Monolayer, adherent
Morphology
Epithelial
Recommended Medium
Quality Control
Fluorescence (DAPI) test: negative; Mycoplasma specific PCR: negative; Bacteria specific PCR: negative
Storage and Shipping
liquid nitrogen vapor phase
Disease
adenocarcinoma
Application
This cell line is a suitable transfection host.
Citation Guidance
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.
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