The LAMA-84 cell line has been established from the peripheral blood of a patient with chronic myeloid leukemia in acute phase. The patient had been treated with busulfan from 1979-1984; blast crisis occurred at the end of March 1984. The cells express megakaryocytic and erythroid markers and respond to the induction of differentiation with DMSO, TPA, butyrate, hemin.
Homo sapiens (Human)
STR DNA Profile
Penta E: 7
Penta D: 10
Human hypertriploid karyotype with 3.6% polyploidy - 73/74(69-77)<3n>XX, -X, +1, -2, +5, +6, +8, +13, -14, +17, +17, -18, +22, +mar, del(7)(p15), der(9)t(9;22)(q34;q11)x2, i(11q), add(13)(q33), del(17)(p12), der(22)t(9;22)(q34;q11)x4 - carries.
Round cells of 25-35 µm diameter
Fluorescence (DAPI) test: negative; Mycoplasma specific PCR: negative; Bacteria
specific PCR: negative
Storage and Shipping
Frozen with 70% medium, 20% FBS, 10% DMSO at about 8 x 10^6 cells/ampoule; ship in dry ice; store in liquid nitrogen
If you use this products in your scientific publication, it should be cited in the publication as: Creative Bioarray cat no. If your paper has been published, please click here to submit the Pub Med ID of your paper to get a coupon.